KRT6B Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP13732c
Background:
The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes isattributed to successive gene duplication events. The genes areexpressed with family members KRT16 and/or KRT17 in the filiformpapillae of the tongue, the stratified epithelial lining of oralmucosa and esophagus, the outer root sheath of hair follicles, andthe glandular epithelia. Mutations in these genes have beenassociated with pachyonychia congenita. The type II cytokeratinsare clustered in a region of chromosome 12q12-q13. [provided byRefSeq].
Other Names:
Keratin, type II cytoskeletal 6B, Cytokeratin-6B, CK-6B, Keratin-6B, K6B, Type-II keratin Kb10, KRT6B, K6B, KRTL1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13732c was selected from the Center region of KRT6B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KRT6B
Gene ID: 3854
Primary Accession: P04259
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes isattributed to successive gene duplication events. The genes areexpressed with family members KRT16 and/or KRT17 in the filiformpapillae of the tongue, the stratified epithelial lining of oralmucosa and esophagus, the outer root sheath of hair follicles, andthe glandular epithelia. Mutations in these genes have beenassociated with pachyonychia congenita. The type II cytokeratinsare clustered in a region of chromosome 12q12-q13. [provided byRefSeq].
Other Names:
Keratin, type II cytoskeletal 6B, Cytokeratin-6B, CK-6B, Keratin-6B, K6B, Type-II keratin Kb10, KRT6B, K6B, KRTL1
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13732c was selected from the Center region of KRT6B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KRT6B
Gene ID: 3854
Primary Accession: P04259
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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