KRT8 polyclonal, anti-human, mouse

Background:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Synonyms: CARD2, CK-8, CK8, CYK8, K2C8, K8, KO

Cellular Location: Cytoplasm Nucleus Nucleus matrix nucleoplasm

Immunogen:
Recombinant protein of human KRT8

Gene Symbol: KRT8

Gene ID: 3856

Swiss prot: P05787

Calculated MW: 54kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.