KRT80 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP10874b
Catalog Number: AC-AP10874b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28277
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28277
Applications: WB
Datasheet
Request Information
Background:
Keratins are intermediate filament proteins responsiblefor the structural integrity of epithelial cells and are subdividedinto epithelial keratins and hair keratins. This gene's expressionprofile shows that it encodes a type II epithelial keratin,although structurally the encoded protein is more like a type IIhair keratin. This protein is involved in cell differentiation,localizing near desmosomal plaques in earlier stages ofdifferentiation but then dispersing throughout the cytoplasm interminally differentiating cells. The type II keratins areclustered in a region of chromosome 12q13. Two transcript variantsencoding two different fully functional isoforms have been foundfor this gene.
Other Names:
Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20, KRT80, KB20
Target/Specificity:
This KRT80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human KRT80.
Antigen Region:
404-432
Antigen Type: Synthetic Peptide
Gene Name: KRT80
Gene ID: 144501
Primary Accession: Q6KB66
NCBI Accession: NP_001074961.1;NP_872313.2
Other Accession: NP_872313.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Keratins are intermediate filament proteins responsiblefor the structural integrity of epithelial cells and are subdividedinto epithelial keratins and hair keratins. This gene's expressionprofile shows that it encodes a type II epithelial keratin,although structurally the encoded protein is more like a type IIhair keratin. This protein is involved in cell differentiation,localizing near desmosomal plaques in earlier stages ofdifferentiation but then dispersing throughout the cytoplasm interminally differentiating cells. The type II keratins areclustered in a region of chromosome 12q13. Two transcript variantsencoding two different fully functional isoforms have been foundfor this gene.
Other Names:
Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20, KRT80, KB20
Target/Specificity:
This KRT80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human KRT80.
Antigen Region:
404-432
Antigen Type: Synthetic Peptide
Gene Name: KRT80
Gene ID: 144501
Primary Accession: Q6KB66
NCBI Accession: NP_001074961.1;NP_872313.2
Other Accession: NP_872313.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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