KRT86 Blocking Peptide (Center)
€363.00
In stock
SKU
AC-BP20108c
Background:
The protein encoded by this gene is a member of thekeratin gene family. As a type II hair keratin, it is a basicprotein which heterodimerizes with type I keratins to form hair andnails. The type II hair keratins are clustered in a region ofchromosome 12q13 and are grouped into two distinct subfamiliesbased on structure similarity. One subfamily, consisting of KRTHB1,KRTHB3, and KRTHB6, is highly related. The other less-relatedsubfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratinsare expressed in the hair follicle; this hair keratin, as well asKRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutationsin this gene and KRTHB1 have been observed in patients with a raredominant hair disease, monilethrix.
Other Names:
Keratin, type II cuticular Hb6, Hair keratin K211, Keratin-86, K86, Type II hair keratin Hb6, Type-II keratin Kb26, KRT86, KRTHB6
Target/Specificity:
The synthetic peptide sequence is selected from aa 315-327 of HUMAN KRT86
Gene Name: KRT86
Gene ID: 3892
Primary Accession: O43790
Other Accession: Q9Z2T6; P78386; P78385; A4FUZ0; Q14533; Q148H4; A6NCN2; NP_002275.1; P15241; P25691
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a member of thekeratin gene family. As a type II hair keratin, it is a basicprotein which heterodimerizes with type I keratins to form hair andnails. The type II hair keratins are clustered in a region ofchromosome 12q13 and are grouped into two distinct subfamiliesbased on structure similarity. One subfamily, consisting of KRTHB1,KRTHB3, and KRTHB6, is highly related. The other less-relatedsubfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratinsare expressed in the hair follicle; this hair keratin, as well asKRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutationsin this gene and KRTHB1 have been observed in patients with a raredominant hair disease, monilethrix.
Other Names:
Keratin, type II cuticular Hb6, Hair keratin K211, Keratin-86, K86, Type II hair keratin Hb6, Type-II keratin Kb26, KRT86, KRTHB6
Target/Specificity:
The synthetic peptide sequence is selected from aa 315-327 of HUMAN KRT86
Gene Name: KRT86
Gene ID: 3892
Primary Accession: O43790
Other Accession: Q9Z2T6; P78386; P78385; A4FUZ0; Q14533; Q148H4; A6NCN2; NP_002275.1; P15241; P25691
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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