KRTHB1 antibody (clone 3B10-5B10), anti-human
€435.00
In stock
SKU
AC-AT2662a
Catalog Number: AC-AT2662a
Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, IHC, IF
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Size: 100 µg
Isotype: mouse IgG2b kappa
Applications: WB, IHC, IF
Request Information AC-AT2662a">Request Information
Background:
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Other Names:
Keratin, type II cuticular Hb1, Hair keratin K29, Keratin, hair, basic, Keratin-81, K81, Metastatic lymph node 137 gene protein, MLN 137, Type II hair keratin Hb1, Type-II keratin Kb21, ghHKb1, ghHb1, KRT81, KRTHB1, MLN137
Antigen Type:
Recombinant Protein
Gene Name: KRT81
Gene ID: 3887
NCBI Accession: NP_002272.2
Primary Accession: Q14533
Other Accession: BC021241
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
Other Names:
Keratin, type II cuticular Hb1, Hair keratin K29, Keratin, hair, basic, Keratin-81, K81, Metastatic lymph node 137 gene protein, MLN 137, Type II hair keratin Hb1, Type-II keratin Kb21, ghHKb1, ghHb1, KRT81, KRTHB1, MLN137
Antigen Type:
Recombinant Protein
Gene Name: KRT81
Gene ID: 3887
NCBI Accession: NP_002272.2
Primary Accession: Q14533
Other Accession: BC021241
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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