KSHV ORF8 polyclonal, anti-virus
€421.00
In stock
SKU
252632
Protein Family: Cellular Antigens
Pathway and Disease: Infectious Diseases, Immune System
Description:
KSHV (Kaposi's sarcoma-associated herpesvirus) belongs to the gamma-2 herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein, acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
Alternate Names: Envelope glycoprotein gB, ORF8, Human herpesvirus 8, HHV-8, Kaposi's sarcoma-associated herpesvirus, HHV8
Application Notes: E: 1:10000; WB: 1:500-1:2000
Accession No.: D0UZL3
Antigen: Synthetic peptide corresponding to a sequence within the C-term region of KSHV ORF8.
Format: Each vial contains 0.1 ml of serum.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Product Citations:
[1] Roy A et al. 2016. J Virol. 90(19): 8822-41. PMID 27466416.
Pathway and Disease: Infectious Diseases, Immune System
Description:
KSHV (Kaposi's sarcoma-associated herpesvirus) belongs to the gamma-2 herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein, acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
Alternate Names: Envelope glycoprotein gB, ORF8, Human herpesvirus 8, HHV-8, Kaposi's sarcoma-associated herpesvirus, HHV8
Application Notes: E: 1:10000; WB: 1:500-1:2000
Accession No.: D0UZL3
Antigen: Synthetic peptide corresponding to a sequence within the C-term region of KSHV ORF8.
Format: Each vial contains 0.1 ml of serum.
Storage:
Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment.
Product Citations:
[1] Roy A et al. 2016. J Virol. 90(19): 8822-41. PMID 27466416.
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