Ksp-Cadherin (Kidney-Specific Cadherin) / CDH16 (clone SPM594 ), anti-human, mouse, rat, dog, rabbit
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SKU
AC-AH10986
Catalog Number: AC-AH10986
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM594
Applications: IHC, IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM594
Applications: IHC, IF, FC
Datasheet
Request Information
Background:
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.ĀKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Other Names:
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Gene Name: CDH16
Gene ID: 1014
Primary Accession: O75309
Other Accession: 1014, 513660
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.ĀKsp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Other Names:
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Gene Name: CDH16
Gene ID: 1014
Primary Accession: O75309
Other Accession: 1014, 513660
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