Ku-70 polyclonal, anti-human

Background:
Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.

Synonyms: CTC75, CTCBF, G22P1, XRCC6, ML8, TLAA

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human Ku-70

Gene Symbol: Ku-70

Gene ID: 2547

Swiss prot: P12956

Calculated MW: 70kDa

Recommended dilution:
WB 1:500-2000, IHC 1:20-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.