Ku-Holo (p70;83 nuclear antigen) (clone EBS-C-003), anti-human

Source:
A BALB/c mouse was immunized with HeLa cells.
Fusion partner: SP2/0.

Specifications:
EBS-C-003 recognizes Ku protein, involved in Pol II-directed transcription by virtue of its DNA binding activity, serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters. It serves as autoantigen in patients with rheumatic diseases.

Species reactivity:
Positive: human.

Applications:
EBS-C-003 can be applied to Immunohistology and, IFA.
Frozen sections: +
Immunofluorescence: +

Positive control: HeLa cells.

References:
- This antibody has not been published