Ku70 (clone 7B1-E12-G4), anti-human, monkey

Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Synonyms: CTC75, CTCBF, G22P1, KU70, ML8, TLAA

Cellular Location: Chromosome Nucleus

Immunogen:
Purified recombinant human Ku70 protein fragments expressed in E.coli.

Gene Symbol: Ku70

Gene ID: 2547

Swiss prot: P12956

Calculated MW: 67kDa

Recommended dilution:
WB 1:1000, ICC 1:200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.