Ku80 (clone 8H1-C3-G10), anti-human, monkey

Background:
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. (provided by RefSeq, Jul 2008).

Synonyms: KARP-1, KARP1, KU80, Ku86, KUB2, NFIV

Cellular Location: Chromosome Nucleus nucleolus

Immunogen:
Purified recombinant human Ku80 protein fragments expressed in E.coli

Gene Symbol: Ku80

Gene ID: 7520

Swiss prot: P13010

Calculated MW: 86kDa

Recommended dilution:
WB 1:1000, ICC 1:400, IP 1:100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.