KV10.1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS5772
Background:
Voltage-gated potassium channels play an essential role in controlling cellular excitability in the nervous system. They regulate a variety of properties including membrane potential as well as the frequency and structure of action potentials. KCNH1 (potassium voltage-gated channel, subfamily H (eag-related), member 1), also known as ether-a-go-go potassium channel 1, voltage-gated potassium channel subunit Kv10.1, EAG, EAG1 or h-eag, is a 989 amino acid multi-pass membrane protein belonging to the potassium channel family and H (Eag) subfamily. KCNH1 is highly expressed in myoblasts and brain, forms two alternatively spliced isoforms and exists as a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. Encoded by a gene located on human chromosome 1, KCNH1 forms a heteromultimer with KCNH5 and also interacts with ALG10.
Alternative Name:
Potassium voltage-gated channel subfamily H member 1, Ether-a-go-go potassium channel 1, EAG channel 1, h-eag, hEAG1, Voltage-gated potassium channel subunit Kv10.1, KCNH1, EAG, EAG1
Application Dilution: WB: 1:500~1:1000
Specificity: KV10.1 polyclonal antibody detects endogenous levels of KV10.1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 762-807 of Human KV10.1.
MW: ~ 111 kDa
Swis Prot.: O95259
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Voltage-gated potassium channels play an essential role in controlling cellular excitability in the nervous system. They regulate a variety of properties including membrane potential as well as the frequency and structure of action potentials. KCNH1 (potassium voltage-gated channel, subfamily H (eag-related), member 1), also known as ether-a-go-go potassium channel 1, voltage-gated potassium channel subunit Kv10.1, EAG, EAG1 or h-eag, is a 989 amino acid multi-pass membrane protein belonging to the potassium channel family and H (Eag) subfamily. KCNH1 is highly expressed in myoblasts and brain, forms two alternatively spliced isoforms and exists as a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. Encoded by a gene located on human chromosome 1, KCNH1 forms a heteromultimer with KCNH5 and also interacts with ALG10.
Alternative Name:
Potassium voltage-gated channel subfamily H member 1, Ether-a-go-go potassium channel 1, EAG channel 1, h-eag, hEAG1, Voltage-gated potassium channel subunit Kv10.1, KCNH1, EAG, EAG1
Application Dilution: WB: 1:500~1:1000
Specificity: KV10.1 polyclonal antibody detects endogenous levels of KV10.1 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 762-807 of Human KV10.1.
MW: ~ 111 kDa
Swis Prot.: O95259
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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