Kv2.1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
KCNB1, also known as Kv2.1 or DRK1, is a protein that, in humans, is encoded by the KCNB1 gene. It is mapped to 20q13.13. KCNB1 is found in cardiomyocytes, skeletal muscles, vascular smooth muscles, placental vasculature, retina, and pancreatic beta-cells. It can mediates the voltage-dependent potassium ion permeability of excitable membranes. KCNB1 represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.

Description:
Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily B member 1 (KCNB1) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
Delayed rectifier potassium channel 1 antibody, Delayed rectifier potassium channel Kv2.1 antibody, DRK 1 antibody, DRK1 antibody, h DRK1 K(+) channel antibody, h-DRK1 antibody, hDRK 1 antibody, hDRK1 antibody, KCB 1 antibody, KCB1 antibody, KCNB1 antibody, KCNB1_HUMAN antibody, KV2.1 antibody, Potassium channel protein DRK1 antibody, Potassium voltage gated channel shab related subfamily member 1 antibody, Potassium voltage-gated channel subfamily B member 1 antibody, Voltage-gated potassium channel subunit Kv2.1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Kv2.1 recombinant protein (Position: V687-I858). Human Kv2.1 shares 88% amino acid (aa) sequences identity with both mouse and rat Kv2.1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.