Kv4.3 polyclonal, anti-mouse, human

Quantity: 100 µg

Background:
Potassium voltage-gated channel subfamily D member 3, also known as Kv4.3, is a protein that in humans is encoded by the KCND3 gene. KCND3 is a member of the potassium channel, voltage-gated, shal-related subfamily. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. It is mapped to 1p13.2. KCND3 is important in membrane repolarization in excitable cells. It contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.

Description:
Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily D member 3 (KCND3) detection. Tested with WB in Human, Mouse.

Synonyms:
KCND 3 antibody, KCND 3L antibody, KCND 3S antibody, Kcnd3 antibody, KCND3_HUMAN antibody, KCND3L antibody, KCND3S antibody, KSHIVB antibody, Kv 4.3 antibody, MGC14203 antibody, MGC142037 antibody, OTTHUMP00000063948 antibody, Potassium ioinic channel Kv4.3 antibody, Potassium voltage gated channel Shal related subfamily member 3 antibody, Potassium voltage gated channel subfamily D member 3 antibody, Potassium voltage-gated channel subfamily D member 3 antibody, Sha1 related potassium channel Kv4.3 antibody, Voltage gated K+ channel antibody, Voltage gated potassium channel Kv4.3 antibody, Voltage gated potassium channel subunit Kv4.3 antibody, Voltage-gated potassium channel subunit Kv4.3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Kv4.3 recombinant protein (Position: M1-H177). Human Kv4.3 shares 100% and 99% amino acid (aa) sequences identity with mouse and rat Kv4.3, respectively.E.coli-derived human Kv4.3 recombinant protein (Position: M1-H177). Human Kv4.3 shares 100% and 99% amino acid (aa) sequences identity with mouse and rat Kv4.3, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.