L-Ficolin (clone ), anti-human

L-Ficolin (clone ), anti-human

€829.00
In stock
SKU
250217
Catalog Nr.: 250217
Size: 0.2 mg
Isotype: Mouse IgG1/k
Applications: E, WB
Datasheet
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Protein Family: Cell Adhesion Molecules,Glycan binding proteins

Pathway and Disease: Immune System,Glycan Biosynthesis and Metabolism

Description:
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease). This antibody reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3).

Alternate Names: Ficolin-A, Ficolin-alpha, M-ficolin, Collagen/fibrinogen domain-containing protein 1

Application Notes: Product Cat. No. 250217 is especially well suited as capture antibody in a sandwich ELISA in combination with Product Cat. No. 250218. Furthermore, Product Cat. No. 250217 reacts with recombinant L-Ficolin coated directly into the microtiter well. E: 1:2,000; WB: 1:1,000

Accession No.: O00602

Antigen: Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein

Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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