L-Ficolin (clone ), anti-human

Protein Family: Cell Adhesion Molecules,Glycan binding proteins

Pathway and Disease: Immune System,Glycan Biosynthesis and Metabolism

Description:
L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease). This antibody reacts specifically with L-Ficolin. No cross reactivity is seen with M-Ficolin (Ficolin-1) and H-Ficolin (Ficolin-3).

Alternate Names: Ficolin-B, Ficolin-beta, L-ficolin, Collagen/fibrinogen domain-containing protein 2, FCN2, Ficolin-2, 37 kDa elastin-binding protein, EBP-37, Hucolin, Serum lectin p35, FCNL

Application Notes: Product Cat. No. 250218 is especially well suited as detecting antibody in a sandwich ELISA in combination with Product Cat. No. 250217. Furthermore, Product Cat. No. 250218 reacts with recombinant L-Ficolin coated directly into the microtiter well. E: 1:4,000; WB: 1:1,000; IP: 5-10 ug/sample

Accession No.: Q15485

Antigen: Purified prokaryote expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein

Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.