L2HGDH polyclonal, anti-human, mouse

Background:
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

Alternative Name:
L2HGA, C14orf160,

Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Specificity: L2HGDH polyclonal antibody detects endogenous levels of L2HGDH protein.

Immunogen:
Recombinant protein of human L2HGDH.

MW: ~ 50 kDa

Swis Prot.: Q9H9P8

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.