L3MBTL2 Polyclonal Antibody

Background:
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
3bt like 2 protein, 3bt like protein, DKFZP761I141 , H-l(3)mbt-like protein 2, H-l(3)mbt-like protein, Hl , Hl(3)mbt like protein , Hl(3)mbtl , L, l(3)mbt like 2 (Drosophila) , l(3)mbt like 2, L(3)mbt-like 2 protein, L(3)mbt-like protein 2, L3MBTL2, Lethal, Lethal(3)malignant brain tumor-like 2 protein, Lethal(3)malignant brain tumor-like protein 2, LMBL2

Immunogen: Fusion protein of human L3MBTL2

Swissprot: Q969R5
Gene Accession: BC017191

Calculated MW: 79 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.2 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.