L3MBTL2 Polyclonal Antibody

Background:
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

Research Area: Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
L3MBTL2, H-l(3)mbt-l, L3MBT

Immunogen: Recombinant fusion protein of human L3MBTL2 (NP_113676.2).

Swissprot: Q969R5
Gene ID: 83746

Calculated MW: 69 kDa/79 kDa
Observed MW: 95 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:1000-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.