LAMA2 antibody (clone 2D4), anti-human
€435.00
In stock
SKU
AC-AT2668a
Catalog Number: AC-AT2668a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, E
Request Information AC-AT2668a">Request Information
Background:
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.
Other Names:
Laminin subunit alpha-2, Laminin M chain, Laminin-12 subunit alpha, Laminin-2 subunit alpha, Laminin-4 subunit alpha, Merosin heavy chain, LAMA2, LAMM
Antigen Type:
Recombinant Protein
Gene Name: LAMA2
Gene ID: 3908
NCBI Accession: NP_000417.2;NP_001073291.1
Primary Accession: P24043
Other Accession: NM_000426
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.
Other Names:
Laminin subunit alpha-2, Laminin M chain, Laminin-12 subunit alpha, Laminin-2 subunit alpha, Laminin-4 subunit alpha, Merosin heavy chain, LAMA2, LAMM
Antigen Type:
Recombinant Protein
Gene Name: LAMA2
Gene ID: 3908
NCBI Accession: NP_000417.2;NP_001073291.1
Primary Accession: P24043
Other Accession: NM_000426
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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