Lamin A/C polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6019
Background:
Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
Alternative Name:
Prelamin-A/C, Lamin-A/C, Lamin A/C, LaminA/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1, Lamin A, LaminA, Lamin-A, Lamin C, LaminC, Lamin-C
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: Lamin A polyclonal antibody detects endogenous levels of Lamin A protein.
Immunogen:
Recombinant full length Human Lamin A.
MW: Predicted band size: 74, 65KDa, Observed band size: 74, 65KDa
Swis Prot.: P02545
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
Alternative Name:
Prelamin-A/C, Lamin-A/C, Lamin A/C, LaminA/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1, Lamin A, LaminA, Lamin-A, Lamin C, LaminC, Lamin-C
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: Lamin A polyclonal antibody detects endogenous levels of Lamin A protein.
Immunogen:
Recombinant full length Human Lamin A.
MW: Predicted band size: 74, 65KDa, Observed band size: 74, 65KDa
Swis Prot.: P02545
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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