Lamin A/C (S17) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS3774
Background:
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology.
Alternative Name:
Prelamin-A/C, Lamin-A/C, Lamin A/C, LaminA/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1, Lamin A, LaminA, Lamin-A, Lamin C, LaminC, Lamin-C
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Lamin A/C (S17) polyclonal antibody detects endogenous levels of Lamin A/C protein.
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human Lamin A.
MW: ~ 74 kDa
Swis Prot.: P02545
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology.
Alternative Name:
Prelamin-A/C, Lamin-A/C, Lamin A/C, LaminA/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1, Lamin A, LaminA, Lamin-A, Lamin C, LaminC, Lamin-C
Application Dilution: WB: 1:500~1:1000, IHC: 1:50~1:200
Specificity: Lamin A/C (S17) polyclonal antibody detects endogenous levels of Lamin A/C protein.
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human Lamin A.
MW: ~ 74 kDa
Swis Prot.: P02545
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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