Lamin A polyclonal, anti-human, mouse, rat antibody

Lamin A polyclonal, anti-human, mouse, rat antibody

€275.00
In stock
SKU
AC-ABV10210-100
Catalog Number: AC-ABV10210-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC
Datasheet

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Background:
Lamins are nuclear membrane structural components that are important in maintaining normal cell functions such as cell cycle control, DNA replication and chromatin organization. Lamin A is specifically cleaved by caspase-6 and therefore serves as a marker for caspase-6 activation. During apoptosis the 70 kDa lamin A is cleaved to a large (40-45 kDa) and small (23 kDa) fragment. The cleavage of lamins results in nuclear disregulation and cell death.

Other Names:
LMNA, HGPS, EMD2, FPLD, CDCD1, LDP1, LGMD1B, IDC, Lamin-A/C, CDDC , LMN1 , CMD1A, PRO1

Primary Accession: P02545

Other Accession: BC033088

Gene Name: LMNA

Gene ID: 4000

Concentration (mg/ml): 0.2 mg/ml
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