Lamin B Receptor rabbit polyclonal, anti-human, rat

Backgroud: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Synonyms: PHA, LMN2R, TDRD18, DHCR14B, LBR

Gene Name: LBR

Gene ID: 3930

SwissProt ID: Q14739

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.