Lamin B1 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6586b
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.
Other Names:
Lamin-B1, LMNB1, LMN2, LMNB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6586b was selected from the C-term region of human Lamin B1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LMNB1
Gene ID: 4001
Primary Accession: P20700
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.
Other Names:
Lamin-B1, LMNB1, LMN2, LMNB
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6586b was selected from the C-term region of human Lamin B1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: LMNB1
Gene ID: 4001
Primary Accession: P20700
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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