Lamin B1 (clone 119D5-F1), anti-human, mouse, rat, bovine, canine, rabbit, sheep, zebrafish

Background:
Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2.

Clone: 119D5-F1

Isotype: Mouse IgG1

Source: 119D5-F1 is a Mouse monoclonal IgG1/k antibody derived by fusion of P3/X63.Ag8.653 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with purified Rat liver lamins.

Reactivity: bovine, canine, human, mouse, rabbit, rat, sheep, zebrafish

Specificity: 119D5-F1 reacts with an epitope loCated C-terminal of residue 231 in lamin B1.

Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.

Applications: Flow Cytometry, Immunocytochemistry, Western blotting

Storage: Store at 4C, or in small aliquots at -20C.