Lamin B1 Mouse mAb

Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Cellular localization: Mitochondrion inner membrane

Specificity: Human

Alternative Names:
ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218

Immunogen: Recombinant Protein

Isotype: Mouse Monoclonal IgG1

Concentration: 1mg/ml

Recommended dilutions: WB 1:2,000-5,000, IP 1:200

Observed band: 68kDa

GeneID: 4001

Swiss-Prot No.: P20700

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only