Lamin B1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Description:
Rabbit IgG polyclonal antibody for Lamin-B1 (LMNB1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
ADLD antibody, lamin B1 antibody, Lamin-B1 antibody, LMN antibody, LMN2 antibody, LMNB antibody, Lmnb1 antibody, LMNB1_HUMAN antibody, MGC111419 antibody, OTTHUMP00000159218 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Lamin B1 recombinant protein (Position: Q266-C583). Human Lamin B1 shares 95.9% and 95% amino acid (aa) sequence identity with mouse and rat Lamin B1, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.