Lamin B1 polyclonal, anti-human, mouse, rat

Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Synonyms: ADLD, LMN, LMN2, LMNB

Cellular Location: Lipid-anchor Nucleoplasmic side Nucleus inner membrane

Immunogen:
Recombinant Protein

Gene Symbol: Lamin B1

Gene ID: 4001

Swiss prot: P20700

Calculated MW: 68/45kDa

Recommended dilution:
WB 1:1000-3000, IHC 1:500-1000,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.