Lamin B2 (clone 8F6-E8-F12), anti-human, mouse

Background:
This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012]

Synonyms: EPM9, LAMB2, LMN2

Cellular Location: Lipid-anchor Nucleoplasmic side Nucleus inner membrane

Immunogen:
Recombinant human Lamin B2 protein.

Gene Symbol: Lamin B2

Gene ID: 84823

Swiss prot: Q03252

Calculated MW: 68kDa

Recommended dilution:
WB 1:500

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.