Lamin B2 (clone LN43), anti-human, mouse, hamster, swine, xenopus, zebrafish

Background:
Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, ie lamin B1 and lamin B2.

Clone: LN43

Isotype: Mouse IgG1

Source: LN43 is a Mouse monoclonal IgG1 antibody derived by fusion of Mouse myeloma cells with spleen cells from a Mouse immunized with the detergent insoluble fraction of potoroo cell line PtK1.

Reactivity: hamster, human, mouse, swine, xenopus, zebrafish

Specificity: LN43 reacts with an epitope loCated in the C-terminal part of lamin B2.

Form: Each vial contains 100ul purified monoclonal antibody in PBS containing 0.09% sodium azide.

Applications: Flow Cytometry, Immunohistochemistry (frozen), Western blotting

Storage: Store at 4C, or in small aliquots at -20C.