Lamin B2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. The LMNB2 gene contains 12 exons. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, is generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.

Description:
Rabbit IgG polyclonal antibody for Lamin-B2 (LMNB2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
LAMB 2 antibody, LAMB2 antibody, Lamin-B2 antibody, LMN 2 antibody, LMN B2 antibody, LMN2 antibody, LMNB 2 antibody, LMNB2 antibody, LMNB2_HUMAN antibody, MGC2721 antibody, RGD1563803 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Lamin B2(580-597aa EEDLFHQQGDPRTTSRGC), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human Lamin B2(580-597aa EEDLFHQQGDPRTTSRGC), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.