Laminin 2 alpha polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Laminin, alpha-2, also known as LAMA2, is a protein that in humans is encoded by the LAMA2 gene. This gene is mapped to 6q22.33. Laminin, an extracellular protein, is a major component of the basement membrane. It is though to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2(merosin) and laminin 4(s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Description:
Rabbit IgG polyclonal antibody for Laminin subunit alpha-2 (LAMA2) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
LAMA 2 antibody, LAMA2 antibody, LAMA2_HUMAN antibody, Laminin alpha 2(merosin congenital muscular dystrophy) antibody, Laminin alpha 2 antibody, Laminin alpha 2 chain antibody, Laminin alpha 2 subunit antibody, Laminin M antibody, Laminin M chain antibody, Laminin subunit alpha-2 antibody, Laminin-12 subunit alpha antibody, Laminin-2 subunit alpha antibody, Laminin-4 subunit alpha antibody, LAMM antibody, Merosin heavy chain antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Laminin 2 alpha(152-170aa WILERSLDDVEYKPWQYHA), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.