Laminin polyclonal, anti-human

Quantity: 100 µg

Background:
Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. Laminins form independent networks and are associated with type IV collagen networks via entactin, fibronectin, and perlecan. They are important and biologically active parts of the basal lamina, influencing cell differentiation, migration, and adhesion, as well as phenotype and survival. Laminins are trimeric proteins that contain an α-chain, a β-chain, and a γ-chain, found in five, four, and three genetic variants, respectively. Laminins critically contribute to cell attachment and differentiation, cell shape and movement, maintenance of tissue phenotype, and promotion of tissue survival.

Description:
Rabbit IgG polyclonal antibody for Laminin subunit gamma-1&Laminin subunit gamma-2&Laminin subunit gamma-3 (LAMC1&LAMC2&LAMC3) detection. Tested with WB, IHC-P, ICC in Human.

Synonyms:
LAMB 2 antibody, LAMB2 antibody, LAMC 1 antibody, LAMC1 antibody, Laminin B2 chain antibody, Laminin gamma 1 antibody, Laminin gamma 1 chain antibody, MGC87297 antibody, 3918 antibody, B2T antibody, BM600 antibody, Cell-scattering factor 140 kDa subunit antibody, CSF 140 kDa subunit antibody, CSF antibody, EBR2 antibody, EBR2A antibody, Epiligrin subunit gamma antibody, Kalinin subunit gamma antibody, Kalinin/nicein/epiligrin 100 kDa subunit antibody, Ladsin 140 kDa subunit antibody, LAMB2T antibody, LAMC2 antibody, LAMC2_HUMAN antibody, Laminin 5 gamma 2 subunit antibody, Laminin B2t chain antibody, Laminin gamma 2 antibody, laminin gamma 2 chain antibody, Laminin subunit gamma-2 antibody, Laminin-5 subunit gamma antibody, LAMNB2 antibody, Large adhesive scatter factor 140 kDa subunit antibody, MGC138491 antibody, MGC141938 antibody, Nicein subunit gamma antibody, NICEIN-100KDA antibody, LAMA 1 antibody, LAMA antibody, LAMA1 antibody, LAMB1 antibody, Lamc3 antibody, LAMC3_HUMAN antibody, Laminin A chain antibody, Laminin alpha 1 antibody, Laminin alpha 1 chain antibody, Laminin B1 chain antibody, Laminin subunit beta 1 antibody, Laminin subunit gamma-3 antibody, Laminin-12 subunit gamma antibody, Laminin-14 subunit gamma antibody, Laminin-15 subunit gamma antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
Peptide mixture of laminin gamma1,2,3(DLNKLNEIEGTLNKAKDEMK; MSELEERARQQRGHLHLLET; LQRKLSLLEQESQQQELQIQ). Laminin gamma has only three subtypes of antibody to gamma1-3 reactive with all isoforms of laminin.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.