Laminnin α3 polyclonal, anti-human

Background:
Laminins are heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. Through interactions with integrins, dystroglycan and other receptors, laminins contribute to cell differentiation, cell shape and migration, and maintenance of tissue phenotypes and survival. Laminin alpha 3/Laminin-5, also known as epiligrin, includes alpha 3, beta 3, and gamma 2 subunits. It is abundant in transitional epithelium, stratified squamous epithelia, lung mucosa and other epithelial glands and contributes to initiation and maintenance of epithelial cell anchorage to the underlying connective tissue. Within aa 21?1713 of the alpha 3 subunit, human and mouse share 77% amino acid sequence identity.

Alternative Name:
E170, LAMA3, E170, Epiligrin 170 kDa subunit, Epiligrin subunit alpha, Kalinin subunit alpha, LAMA3, LAMA3A, Laminin 5 alpha3, Laminin A3, laminin alpha 3, laminin alpha3, Laminin subunit alpha-3, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, laminin5 alpha 3, Laminin5 alpha3, LAMNA, LOCS, Nicein subunit alpha,

Application Dilution:
WB:1:1,000-1:2,000
ICC:1:100-1:500

Specificity: Laminnin α3 polyclonal antibody detects endogenous levels of Laminnin α3 protein.

Immunogen:
recombinant protein

MW: 367 kDa

Swiss-Prot: Q16787(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.