LARG Polyclonal Antibody

Background:
Rho guanine nucleotide exchange factor 12(ARHGEF12) Homo sapiens Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Alternative Names:
ARHGEF12, KIAA0382, LARG, Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF

Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 173

GeneID: ARHGEF12

Storage: -20°C/1 year

NOTE: For Research Use Only