LARP1 polyclonal, anti-human
€388.00
In stock
SKU
BS71974
Background:
La-related protein 1 (LARP1), also known as KIAA0731, is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3 β, 14-3-3 γ, 14-3-3 θ and 14-3-3 . Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.
Alternative Name:
LARP, La-related protein 1, KIAA0731
Application Dilution: WB: 1:500 - 1:2000
Specificity: LARP1 polyclonal antibody detects endogenous levels of LARP1 protein.
Immunogen:
Recombinant Protein of human LARP1
MW: 123kDa
Swis Prot.: Q6PKG0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
La-related protein 1 (LARP1), also known as KIAA0731, is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3 β, 14-3-3 γ, 14-3-3 θ and 14-3-3 . Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing.
Alternative Name:
LARP, La-related protein 1, KIAA0731
Application Dilution: WB: 1:500 - 1:2000
Specificity: LARP1 polyclonal antibody detects endogenous levels of LARP1 protein.
Immunogen:
Recombinant Protein of human LARP1
MW: 123kDa
Swis Prot.: Q6PKG0
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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