LASP1 polyclonal, anti-human

Quantity: 100 µg

Background:
LASP1(LIM and SH3 domain protein 1), also known as LASP1, is a protein that in humans is encoded by the LASP1 gene. This gene encodes a member of a LIM protein subfamily which is characterized by a LIM motif and a domain of Src homology region 3. This protein functions as an actin-binding protein and possibly in cytoskeletal organization. LASP1 has been shown to interact with Zyxin. Tomasetto et al.(1995) mapped the LASP1 gene to chromosome 17q11-q21.3 by radioactive in situ hybridization. Northern blot analysis revealed that LASP1 mRNA was expressed at a basal level in all normal tissues examined and overexpressed in 8% of primary breast cancers. In most of these cancers, LASP1 and ERBB2 were simultaneously overexpressed.

Description:
Rabbit IgG polyclonal antibody for LIM and SH3 domain protein 1 (LASP1) detection. Tested with WB, IHC-P in Human.

Synonyms:
LASP 1 antibody, LASP-1 antibody, LASP1 antibody, LASP1_HUMAN antibody, LIM and SH3 domain protein 1 antibody, LIM and SH3 protein 1 antibody, Metastatic lymph node gene 50 protein antibody, MLN 50 antibody, MLN50 antibody, OTTHUMP00000164238 antibody, OTTHUMP00000164239 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human LASP1(152-168aa YRRPLEQQQPHHIPTSA).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.