LAT antibody (clone 3B11-1D5), anti-human
€435.00
In stock
SKU
AC-AT2679a
Catalog Number: AC-AT2679a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, E
Request Information AC-AT2679a">Request Information
Background:
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT
Antigen Type:
Recombinant Protein
Gene Name: LAT
Gene ID: 27040
NCBI Accession: NP_001014987.1;NP_001014988.1;NP_001014989.2;NP_055202.1
Primary Accession: O43561
Other Accession: BC011563
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Other Names:
Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT
Antigen Type:
Recombinant Protein
Gene Name: LAT
Gene ID: 27040
NCBI Accession: NP_001014987.1;NP_001014988.1;NP_001014989.2;NP_055202.1
Primary Accession: O43561
Other Accession: BC011563
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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