LAT polyclonal, anti-human

Quantity: 100 µg

Background:
Linker for activation of T cells, also known as LAT, is a protein which in humans is encoded by the LAT gene. This gene is mapped to 16p11.2. The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor(TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement.

Description:
Rabbit IgG polyclonal antibody for Linker for activation of T-cells family member 1 (LAT) detection. Tested with WB, IHC-P, ICC in Human.

Synonyms:
36 kDa phospho tyrosine adapter protein antibody, 36 kDa phospho-tyrosine adapter protein antibody, 36 kDa phospho-tyrosine adaptor protein antibody, LAT 1 antibody, lat antibody, LAT_HUMAN antibody, LAT1 antibody, Linker for activation of T cells antibody, Linker for activation of T cells family member 1 antibody, linker for activation of T cells, transmembrane adaptor antibody, Linker for activation of T-cells family member 1 antibody, p36 38 antibody, p36-38 antibody, pp36 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human LAT(242-262aa QEAEEVEEEGAPDYENLQELN), different from the related mouse and rat sequences by six amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P, ICC

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.