LBR polyclonal, anti-human

Background:
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. 

Synonyms: PHA, LMN2R, TDRD18, DHCR14B

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human LBR

Gene Symbol: LBR

Gene ID: 3930

Swiss prot: Q14739

Calculated MW: 71 kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.