LBR Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
DHCR 14B, DHCR14B, Integral nuclear envelope inner membrane protein, Lamin-B receptor, LBR, LBR, LMN 2R, LMN2R, MGC9041, PHA, PRO0650

Immunogen: Recombinant protein of human LBR

Swissprot: Q14739
Gene Accession: BC020079

Calculated MW: 71 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-160482