LBR Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
LBR, DHCR14B, LMN2R, PHA, TDRD18

Immunogen: Recombinant fusion protein of human LBR (NP_002287.2).

Swissprot: Q14739
Gene ID: 3930

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.