Lck polyclonal, anti-human, mouse, rat antibody
€275.00
In stock
SKU
AC-ABV10369-100
Catalog Number: AC-ABV10369-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Background:
Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in some murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations s µggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease.
Other Names:
LCK , p56-LCK , p56lck , YT16 , pp58lck , LSK
Primary Accession: P06239
Gene Name: LCK
Gene ID: 3932
Concentration (mg/ml): 0.5 mg/ml
Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in some murine lymphomas. In human studies, it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations s µggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease.
Other Names:
LCK , p56-LCK , p56lck , YT16 , pp58lck , LSK
Primary Accession: P06239
Gene Name: LCK
Gene ID: 3932
Concentration (mg/ml): 0.5 mg/ml
| Is Featured? | No |
|---|
Write Your Own Review