LCP1 polyclonal, anti-human, mouse

Background:
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

Synonyms: CP64, HEL-S-37, L-PLASTIN, LC64P, LPL, PLS2

Cellular Location: Cell junction Cell projection Cytoplasm Cytoplasmic side Peripheral membrane protein cytoskeleton ruffle membrane

Immunogen:
Recombinant protein of human LCP1

Gene Symbol: LCP1

Gene ID: 3936

Swiss prot: P13796

Calculated MW: 70kDa

Recommended dilution:
WB 1:500-2000, IP 1:20-50,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.