LCP1 polyclonal (Center), anti-human

LCP1 polyclonal (Center), anti-human

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In stock
SKU
AC-AP18836c
Catalog Number: AC-AP18836c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39488
Applications: WB
Datasheet

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Background:
Plastins are a family of actin-binding proteins that areconserved throughout eukaryote evolution and expressed in mosttissues of higher eukaryotes. In humans, two ubiquitous plastinisoforms (L and T) have been identified. Plastin 1 (otherwise knownas Fimbrin) is a third distinct plastin isoform which isspecifically expressed at high levels in the small intestine. The Lisoform is expressed only in hemopoietic cell lineages, while the Tisoform has been found in all other normal cells of solid tissuesthat have replicative potential (fibroblasts, endothelial cells,epithelial cells, melanocytes, etc.). However, L-plastin has beenfound in many types of malignant human cells of non-hemopoieticorigin suggesting that its expression is induced accompanyingtumorigenesis in solid tissues.

Other Names:
Plastin-2, L-plastin, LC64P, Lymphocyte cytosolic protein 1, LCP-1, LCP1, PLS2

Target/Specificity:
This LCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 306-335 amino acids from the Central region of human LCP1.

Antigen Region:
306-335

Antigen Type: Synthetic Peptide

Gene Name: LCP1
Gene ID: 3936
Primary Accession: P13796
NCBI Accession: NP_002289.2
Other Accession: Q61233; NP_002289.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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