LDB1 Polyclonal Antibody

Background:
Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).

Research Area: Cancer, Epigenetics and Nuclear Signaling, Neuroscience

Synonyms:
Carboxyl Terminal LIM Domain Binding 2, Carboxyl-terminal LIM domain-binding protein 2, CLIM 2, CLIM-2, hLdb1, LDB-1, ldb1, LDB1, LIM Domain Binding 1, LIM domain binding factor CLIM2 , LIM domain-binding factor CLIM2, LIM domain-binding protein 1, NLI, Nuclear LIM Domain Interactor, Nuclear LIM interactor, xldb1

Immunogen: Fusion protein of human LDB1

Swissprot: Q86U70
Gene Accession: BC000482

Calculated MW: 47 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.26 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:70-1:350, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.