LDB3 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP17020c
Background:
This gene encodes a PDZ domain-containing protein. PDZmotifs are modular protein-protein interaction domains consistingof 80-120 amino acid residues. PDZ domain-containing proteinsinteract with each other in cytoskeletal assembly or with otherproteins involved in targeting and clustering of membrane proteins.The protein encoded by this gene interacts with alpha-actinin-2through its N-terminal PDZ domain and with protein kinase C via itsC-terminal LIM domains. The LIM domain is a cysteine-rich motifdefined by 50-60 amino acids containing two zinc-binding modules.This protein also interacts with all three members of the myozeninfamily. Mutations in this gene have been associated withmyofibrillar myopathy and dilated cardiomyopathy. Alternativelyspliced transcript variants encoding different isoforms have beenidentified; all isoforms have N-terminal PDZ domains while onlylonger isoforms (1, 2 and 5) have C-terminal LIM domains. [providedby RefSeq].
Other Names:
LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein, LDB3 (HGNC:15710)
Gene Name: LDB3 (HGNC:15710)
Gene ID: 11155
Primary Accession: O75112
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a PDZ domain-containing protein. PDZmotifs are modular protein-protein interaction domains consistingof 80-120 amino acid residues. PDZ domain-containing proteinsinteract with each other in cytoskeletal assembly or with otherproteins involved in targeting and clustering of membrane proteins.The protein encoded by this gene interacts with alpha-actinin-2through its N-terminal PDZ domain and with protein kinase C via itsC-terminal LIM domains. The LIM domain is a cysteine-rich motifdefined by 50-60 amino acids containing two zinc-binding modules.This protein also interacts with all three members of the myozeninfamily. Mutations in this gene have been associated withmyofibrillar myopathy and dilated cardiomyopathy. Alternativelyspliced transcript variants encoding different isoforms have beenidentified; all isoforms have N-terminal PDZ domains while onlylonger isoforms (1, 2 and 5) have C-terminal LIM domains. [providedby RefSeq].
Other Names:
LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein, LDB3 (HGNC:15710)
Gene Name: LDB3 (HGNC:15710)
Gene ID: 11155
Primary Accession: O75112
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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