LDB3 antibody (clone 3C8), anti-human
€435.00
In stock
SKU
AC-AT2686a
Catalog Number: AC-AT2686a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
Request Information AC-AT2686a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
Request Information AC-AT2686a">Request Information
Background:
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.
Other Names:
LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein, LDB3 (HGNC:15710)
Antigen Type:
Recombinant Protein
Gene Name: LDB3 (HGNC:15710)
Gene ID: 11155
NCBI Accession: NP_001073583.1;NP_001073584.1;NP_001073585.1;NP_001165081.1;NP_001165082.1;NP_009009.1
Primary Accession: O75112
Other Accession: BC010929
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.
Other Names:
LIM domain-binding protein 3, Protein cypher, Z-band alternatively spliced PDZ-motif protein, LDB3 (HGNC:15710)
Antigen Type:
Recombinant Protein
Gene Name: LDB3 (HGNC:15710)
Gene ID: 11155
NCBI Accession: NP_001073583.1;NP_001073584.1;NP_001073585.1;NP_001165081.1;NP_001165082.1;NP_009009.1
Primary Accession: O75112
Other Accession: BC010929
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review