LDHA polyclonal, anti-human, mouse, rat

Background:
Lactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.

Alternative Name:
LDH-A, LDH-M, Cell proliferation-inducing gene 19 protein, GSD11, L lactate dehydrogenase A chain, L-lactate dehydrogenase A chain, l7R2, Lactate dehydrogenase 1, A chain, Lactate dehydrogenase A, Lactate dehydrogenase A4, Lactate dehydrogenase M, LDH A, LDH M, LDH muscle subunit, LDH muscle subunit, M LDH, LDH-A, LDH-M, LDH1, ldha, LDHA, LDHM, OTTMUSP00000017774, PIG19, Proliferation-inducing gene 19, Renal carcinoma antigen NY-REN-59,

Application Dilution:
WB:1:500
IHC:1:200
FC:1:100-1:200

Specificity: LDHA polyclonal antibody detects endogenous levels of LDHA protein.

Immunogen:
peptide

MW: 37 kDa

Swiss-Prot: P00338

Purification & Purity:
Peptide affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.